Title : Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

Pub. Date : 1998 Jul 1

PMID : 9634557






2 Functional Relationships(s)
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1 Furthermore, ventricular infusion of Z-DEVD-FMK, a caspase-3 inhibitor, decreased caspase-3 activity in the hippocampus and significantly reduced cell death and DNA fragmentation in the CA1 sector up to 7 d after ischemia. benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone caspase 3 Rattus norvegicus
2 Furthermore, ventricular infusion of Z-DEVD-FMK, a caspase-3 inhibitor, decreased caspase-3 activity in the hippocampus and significantly reduced cell death and DNA fragmentation in the CA1 sector up to 7 d after ischemia. benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone caspase 3 Rattus norvegicus