Pub. Date : 1998 Mar 16
PMID : 9500792
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells. | ammonium ferrous sulfate | sphingomyelin phosphodiesterase 1 | Homo sapiens |
2 | Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells. | Gangliosides | sphingomyelin phosphodiesterase 1 | Homo sapiens |
3 | Inefficient apoptosis is due to lack of ASM activity, because proximal signaling from Fas in NPD lymphoblasts is not impaired and apoptosis can be efficiently triggered by passing the ASM defect with exogenous ceramides. | Ceramides | sphingomyelin phosphodiesterase 1 | Homo sapiens |