Title : Purification and preliminary characterization of an Fc epsilon-receptor-activated protein-tyrosine phosphatase from mast cells.

Pub. Date : 1998 Feb 1

PMID : 9490073






3 Functional Relationships(s)
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Protein Name
Organism
1 It is apparently mediated by protein kinase C (PKC) since phorbol myristate induced an additive increase in the MpII PTP activity to that induced by antigen. Phorbol 13-myristate protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus
2 Also, treatment with the PKC-specific inhibitor bisindolylmaleimide suppressed the antigen-induced MpII PTP activity enhancement. bisindolylmaleimide protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus
3 PKC involvement was further supported by the finding that the MpII PTP 45-kDa protein underwent seryl phosphorylation following antigen stimulation. seryl protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus