Title : Different interactions of cardiac and skeletal muscle ryanodine receptors with FK-506 binding protein isoforms.

Pub. Date : 1997 May

PMID : 9176165






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both FKBP12 and FKBP12.6 rebind to FKBP-depleted RyR1 and restore its quiescent channel behavior by altering ligand sensitivity, as studied by single-channel recordings in planar lipid bilayers, and macroscopic behavior of the channels (ryanodine binding and net energized Ca2- uptake). Ryanodine FKBP prolyl isomerase 1B Homo sapiens