Title : Effect of C-peptide on insulin and glucagon release by isolated perfused rat pancreas.

Pub. Date : 1997 Apr

PMID : 9137904






1 Functional Relationships(s)
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1 Administration of rat C-peptide (0.1 mumol/l) to isolated rat pancrease failed to inhibit insulin release induced by a high concentration of D-glucose (11.1 mmol/l) but prevented the progressive increase in insulin output otherwise observed during prolonged perfusion in the presence of 3.3 mmol/l glucose and 5.0 mmol/l L-arginine. Arginine insulin 2 Rattus norvegicus