Pub. Date : 1997 Apr 11
PMID : 9125410
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activation of CPP32 (caspase-3/Yama/apopain)-like proteolytic activity, a key mediator of apoptosis, precedes neuronal death, and polyamines prevented an increase in this activity. | Polyamines | caspase 3 | Rattus norvegicus |
| 2 | Activation of CPP32 (caspase-3/Yama/apopain)-like proteolytic activity, a key mediator of apoptosis, precedes neuronal death, and polyamines prevented an increase in this activity. | Polyamines | caspase 3 | Rattus norvegicus |
| 3 | Activation of CPP32 (caspase-3/Yama/apopain)-like proteolytic activity, a key mediator of apoptosis, precedes neuronal death, and polyamines prevented an increase in this activity. | Polyamines | caspase 3 | Rattus norvegicus |
| 4 | These results demonstrate that polyamines protect neurons from apoptotic cell death through both NMDA receptor-dependent and -independent mechanisms, acting upstream from the activation of CPP32-like protease(s). | Polyamines | caspase 3 | Rattus norvegicus |