Title : The contribution of nitric oxide to endotoxin-induced ocular inflammation: interaction with sensory nerve fibres.

Pub. Date : 1996 Jul

PMID : 8832083






2 Functional Relationships(s)
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1 Pretreatment with the NO synthase (NOS) inhibitor, NG-nitro-L-arginine (L-NAME, 200 mg kg-1) given by intravenous injection, inhibited the endotoxin-evoked responses; the AFR was 16.5 +/- 1.9 (n = 8, P < 0.001) and the conjunctival hyperaemia was abolished. Nitroarginine nitric oxide synthase, brain Oryctolagus cuniculus
2 Pretreatment with the NO synthase (NOS) inhibitor, NG-nitro-L-arginine (L-NAME, 200 mg kg-1) given by intravenous injection, inhibited the endotoxin-evoked responses; the AFR was 16.5 +/- 1.9 (n = 8, P < 0.001) and the conjunctival hyperaemia was abolished. NG-Nitroarginine Methyl Ester nitric oxide synthase, brain Oryctolagus cuniculus