Pub. Date : 1995 Sep
PMID : 8786250
13 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Procainamide administration often results in excessively high serum N-acetylprocainamide (NAPA) concentrations and subtherapeutic serum procainamide concentrations. | Procainamide | NSF attachment protein alpha | Homo sapiens |
| 2 | Inhibition of N-acetylation of procainamide may prevent accumulation of excessive NAPA while maintaining therapeutic serum procainamide concentrations. | Nitrogen | NSF attachment protein alpha | Homo sapiens |
| 3 | Inhibition of N-acetylation of procainamide may prevent accumulation of excessive NAPA while maintaining therapeutic serum procainamide concentrations. | Procainamide | NSF attachment protein alpha | Homo sapiens |
| 4 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | 4-Aminobenzoic Acid | NSF attachment protein alpha | Homo sapiens |
| 5 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | 4-Aminobenzoic Acid | NSF attachment protein alpha | Homo sapiens |
| 6 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | 4-Aminobenzoic Acid | NSF attachment protein alpha | Homo sapiens |
| 7 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | 4-Aminobenzoic Acid | NSF attachment protein alpha | Homo sapiens |
| 8 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | Procainamide | NSF attachment protein alpha | Homo sapiens |
| 9 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | Procainamide | NSF attachment protein alpha | Homo sapiens |
| 10 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | Procainamide | NSF attachment protein alpha | Homo sapiens |
| 11 | However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. | Procainamide | NSF attachment protein alpha | Homo sapiens |
| 12 | Although PABA inhibits metabolic conversion of procainamide to NAPA, it also impairs the renal clearance of NAPA (but not procainamide) in healthy subjects. | 4-Aminobenzoic Acid | NSF attachment protein alpha | Homo sapiens |
| 13 | Although PABA inhibits metabolic conversion of procainamide to NAPA, it also impairs the renal clearance of NAPA (but not procainamide) in healthy subjects. | 4-Aminobenzoic Acid | NSF attachment protein alpha | Homo sapiens |