PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8786250-1 1995 Procainamide administration often results in excessively high serum N-acetylprocainamide (NAPA) concentrations and subtherapeutic serum procainamide concentrations. Procainamide 0-12 NSF attachment protein alpha Homo sapiens 90-94 8786250-2 1995 Inhibition of N-acetylation of procainamide may prevent accumulation of excessive NAPA while maintaining therapeutic serum procainamide concentrations. Nitrogen 14-15 NSF attachment protein alpha Homo sapiens 82-86 8786250-2 1995 Inhibition of N-acetylation of procainamide may prevent accumulation of excessive NAPA while maintaining therapeutic serum procainamide concentrations. Procainamide 31-43 NSF attachment protein alpha Homo sapiens 82-86 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. 4-Aminobenzoic Acid 21-25 NSF attachment protein alpha Homo sapiens 84-88 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. 4-Aminobenzoic Acid 21-25 NSF attachment protein alpha Homo sapiens 124-128 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. 4-Aminobenzoic Acid 21-25 NSF attachment protein alpha Homo sapiens 124-128 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. 4-Aminobenzoic Acid 21-25 NSF attachment protein alpha Homo sapiens 124-128 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. Procainamide 46-58 NSF attachment protein alpha Homo sapiens 84-88 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. Procainamide 46-58 NSF attachment protein alpha Homo sapiens 124-128 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. Procainamide 46-58 NSF attachment protein alpha Homo sapiens 124-128 8786250-10 1995 However, concomitant PABA administration with procainamide resulted in increases in NAPA AUC0-00 and t1/2 and reductions in NAPA Ke, procainamide acetylation (NAPA formation) clearance, and NAPA renal clearance. Procainamide 46-58 NSF attachment protein alpha Homo sapiens 124-128 8786250-11 1995 Although PABA inhibits metabolic conversion of procainamide to NAPA, it also impairs the renal clearance of NAPA (but not procainamide) in healthy subjects. 4-Aminobenzoic Acid 9-13 NSF attachment protein alpha Homo sapiens 63-67 8786250-11 1995 Although PABA inhibits metabolic conversion of procainamide to NAPA, it also impairs the renal clearance of NAPA (but not procainamide) in healthy subjects. 4-Aminobenzoic Acid 9-13 NSF attachment protein alpha Homo sapiens 108-112