Pub. Date : 1996
PMID : 8743975
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These results indicate that peroxidation of internal membrane lipids, a decrease in the intracellular GSH levels and the integrity of the plasma membrane are all important for the UVA-induction of heme oxygenase-1. | Glutathione | heme oxygenase 1 | Homo sapiens |
| 2 | The nonenzymatic lipid peroxidation product 4-hydroxynonenal induces heme oxygenase-1 mRNA up to 40-fold and the phospholipase metabolites diacylglycerol and arachidonic acid induce this mRNA by three-to sixfold above basal levels. | 4-hydroxy-2-nonenal | heme oxygenase 1 | Homo sapiens |
| 3 | We also demonstrate that the cyclooxygenase metabolites of arachidonic acid are important for the UVA-activation of the heme oxygenase-1 gene. | Arachidonic Acid | heme oxygenase 1 | Homo sapiens |