Title : Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors.

Pub. Date : 1996 Jun 5

PMID : 8660357






4 Functional Relationships(s)
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1 Both the cytokine tumor necrosis factor alpha (TNF-alpha) and the phosphatase inhibitor calyculin A have been shown to induce rapid phosphorylation and degradation of I kappa B alpha. calyculin A NFKB inhibitor alpha Homo sapiens
2 Interestingly, phosphorylation of I kappa B alpha induced by both inducers involves serine-32 and serine-36 of I kappa B alpha. Serine NFKB inhibitor alpha Homo sapiens
3 Interestingly, phosphorylation of I kappa B alpha induced by both inducers involves serine-32 and serine-36 of I kappa B alpha. Serine NFKB inhibitor alpha Homo sapiens
4 Interestingly, phosphorylation of I kappa B alpha induced by both inducers involves serine-32 and serine-36 of I kappa B alpha. Serine NFKB inhibitor alpha Homo sapiens