Title : Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.

Pub. Date : 1995 Oct

PMID : 8654202






2 Functional Relationships(s)
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1 In addition, the respective omega-OH finasteride and omega-oic acid finasteride metabolites were generated only by microsomes containing recombinant CYP3A4, but not the other isozymes (CYP1A1, CYP2B6, CYP2C8, CYP2C9, CYP2D6, and CYP2E1). omega-oh finasteride cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 In addition, the respective omega-OH finasteride and omega-oic acid finasteride metabolites were generated only by microsomes containing recombinant CYP3A4, but not the other isozymes (CYP1A1, CYP2B6, CYP2C8, CYP2C9, CYP2D6, and CYP2E1). omega-oic acid finasteride cytochrome P450 family 2 subfamily C member 9 Homo sapiens