Title : X-ray structure of a decameric cyclophilin-cyclosporin crystal complex.

Pub. Date : 1993 Jan 7

PMID : 8421501






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Human cyclophilin A (CypA), a ubiquitous intracellular protein of 165 amino acids, is the major receptor for the cyclic undecapeptide immunosuppressant drug cyclosporin A (CsA), which prevents allograft rejection after transplant surgery and is efficacious in the field of autoimmune diseases. Cyclosporine peptidylprolyl isomerase A Homo sapiens
2 Human cyclophilin A (CypA), a ubiquitous intracellular protein of 165 amino acids, is the major receptor for the cyclic undecapeptide immunosuppressant drug cyclosporin A (CsA), which prevents allograft rejection after transplant surgery and is efficacious in the field of autoimmune diseases. Cyclosporine peptidylprolyl isomerase A Homo sapiens
3 Here we describe the crystal structure of a decameric CypA-CsA complex. Cyclosporine peptidylprolyl isomerase A Homo sapiens