Title : SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist.

Pub. Date : 1994 Aug 16

PMID : 8058755






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SB 209670, which was rationally designed using conformational models of ET-1, selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki = 0.2 and 18 nM, respectively). Antimony endothelin 1 Homo sapiens
2 SB 209670, which was rationally designed using conformational models of ET-1, selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki = 0.2 and 18 nM, respectively). Antimony endothelin 1 Homo sapiens
3 SB 209670, which was rationally designed using conformational models of ET-1, selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki = 0.2 and 18 nM, respectively). Antimony endothelin receptor type B Homo sapiens