Title : Effect of tubulin on the activity of the muscle isoenzyme of lactate dehydrogenase.

Pub. Date : 1994 Dec

PMID : 7986093






5 Functional Relationships(s)
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Protein Name
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1 The interaction between muscle-type lactate dehydrogenase (LDHm) and tubulin was investigated by monitoring the combined effect of NADH and tubulin on steady-state kinetics and the combined effect of NADH and pH on complex formation between tubulin and the enzyme. NAD lactate dehydrogenase A Homo sapiens
2 The interaction between muscle-type lactate dehydrogenase (LDHm) and tubulin was investigated by monitoring the combined effect of NADH and tubulin on steady-state kinetics and the combined effect of NADH and pH on complex formation between tubulin and the enzyme. NAD lactate dehydrogenase A Homo sapiens
3 In contrast to the absence of tubulin, its presence induced a modification of the kinetic behavior of LDHm; i.e., the velocity dependence on NADH concentration displayed a marked sigmoid response. NAD lactate dehydrogenase A Homo sapiens
4 NAD+ was much less effective than NADH in dissociating LDHm from immobilized tubulin. NAD lactate dehydrogenase A Homo sapiens
5 NAD+ was much less effective than NADH in dissociating LDHm from immobilized tubulin. NAD lactate dehydrogenase A Homo sapiens