Title : [Expression of human multidrug resistance gene (mdr1) cDNA in murine ES cells and in chimeric mice].

Pub. Date : 1993 Dec

PMID : 7912874






1 Functional Relationships(s)
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1 Human multidrug resistance gene (mdr1) was introduced into mouse embryonic stem cells (ES-5 line) by calcium phosphate mediated transfection, and transfected ES-5 cells were then selected by stepwise increase in colchicine concentration (30, 50, 100, and 200 ng/ml respectively). calcium phosphate ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus