Pub. Date : 1994 Oct
PMID : 7883762
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intracellular calcium dependent activation of p72syk in platelets. | Calcium | spleen associated tyrosine kinase | Homo sapiens |
| 2 | When washed porcine platelets were stimulated with ionophore A23187 and the activity of p72syk was assessed by means of an immunoprecipitation kinase assay, A23187 caused a time- and dose-dependent increase in the specific activity of p72syk. | Calcimycin | spleen associated tyrosine kinase | Homo sapiens |
| 3 | When washed porcine platelets were stimulated with ionophore A23187 and the activity of p72syk was assessed by means of an immunoprecipitation kinase assay, A23187 caused a time- and dose-dependent increase in the specific activity of p72syk. | Calcimycin | spleen associated tyrosine kinase | Homo sapiens |
| 4 | These results indicate that A23187-induced activation of p72syk is independent of the formation of endoperoxide/thromboxane A2, released ADP and extracellular Ca2+, suggesting the existence of a novel pathway for activation of p72syk. | Calcimycin | spleen associated tyrosine kinase | Homo sapiens |
| 5 | These results indicate that A23187-induced activation of p72syk is independent of the formation of endoperoxide/thromboxane A2, released ADP and extracellular Ca2+, suggesting the existence of a novel pathway for activation of p72syk. | Calcimycin | spleen associated tyrosine kinase | Homo sapiens |
| 6 | These results indicate that A23187-induced activation of p72syk is independent of the formation of endoperoxide/thromboxane A2, released ADP and extracellular Ca2+, suggesting the existence of a novel pathway for activation of p72syk. | Adenosine Diphosphate | spleen associated tyrosine kinase | Homo sapiens |
| 7 | Furthermore, evidence is presented which indicates a synergistic effect of A23187 and thrombin on the activation of p72syk, and an inhibitory effect of pretreatment with phorbol 12-myristate 13-acetate, a protein kinase C activator, on the activation of p72syk induced by either A23187 or thrombin. | Calcimycin | spleen associated tyrosine kinase | Homo sapiens |
| 8 | Furthermore, evidence is presented which indicates a synergistic effect of A23187 and thrombin on the activation of p72syk, and an inhibitory effect of pretreatment with phorbol 12-myristate 13-acetate, a protein kinase C activator, on the activation of p72syk induced by either A23187 or thrombin. | Tetradecanoylphorbol Acetate | spleen associated tyrosine kinase | Homo sapiens |
| 9 | Furthermore, evidence is presented which indicates a synergistic effect of A23187 and thrombin on the activation of p72syk, and an inhibitory effect of pretreatment with phorbol 12-myristate 13-acetate, a protein kinase C activator, on the activation of p72syk induced by either A23187 or thrombin. | Calcimycin | spleen associated tyrosine kinase | Homo sapiens |