Protein Name spleen associated tyrosine kinase
Organism Homo sapiens
Gene ID 6850
Gene Symbol


UniProt P43405 (KSYK_HUMAN), A0A024R244 (A0A024R244_HUMAN), A0A024R273 (A0A024R273_HUMAN)
Relationships Total Number of functionally related compound(s) : 486
Total Number of Articles : 1006

spleen associated tyrosine kinase

Gene Summary

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

  • tyrosine-protein kinase SYK
  • spleen tyrosine kinase
  • IMD82
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