| Protein Name | spleen associated tyrosine kinase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6850 |
| Gene Symbol | SYK |
| UniProt | P43405 (KSYK_HUMAN), A0A024R244 (A0A024R244_HUMAN), A0A024R273 (A0A024R273_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
486
Total Number of Articles : 1006 |
Description |
spleen associated tyrosine kinase |
| Gene Summary |
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
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