Title : Tissue specificity and mechanism of vitamin D receptor up-regulation during dietary phosphorus restriction in the rat.

Pub. Date : 1995 Feb

PMID : 7754807






8 Functional Relationships(s)
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1 Tissue specificity and mechanism of vitamin D receptor up-regulation during dietary phosphorus restriction in the rat. Phosphorus vitamin D receptor Rattus norvegicus
2 Dietary phosphorus restriction up-regulates intestinal vitamin D receptor (VDR), but the tissue specificity of the up-regulation and the mechanism of receptor accumulation remain unknown. Phosphorus vitamin D receptor Rattus norvegicus
3 Dietary phosphorus restriction up-regulates intestinal vitamin D receptor (VDR), but the tissue specificity of the up-regulation and the mechanism of receptor accumulation remain unknown. Phosphorus vitamin D receptor Rattus norvegicus
4 The results of these studies indicate that VDR up-regulation during dietary phosphorus restriction is tissue-specific and that the mechanism of the up-regulation is time-dependent. Phosphorus vitamin D receptor Rattus norvegicus
5 Acutely (D1-D5), phosphorus restriction up-regulates intestinal VDR through increased VDR gene expression, whereas chronic (D5-D10) phosphorus restriction appears to alter VDR metabolism through nongenomic mechanisms that are consistent with prolongation of the half-life of the receptor. Phosphorus vitamin D receptor Rattus norvegicus
6 Acutely (D1-D5), phosphorus restriction up-regulates intestinal VDR through increased VDR gene expression, whereas chronic (D5-D10) phosphorus restriction appears to alter VDR metabolism through nongenomic mechanisms that are consistent with prolongation of the half-life of the receptor. Phosphorus vitamin D receptor Rattus norvegicus
7 Acutely (D1-D5), phosphorus restriction up-regulates intestinal VDR through increased VDR gene expression, whereas chronic (D5-D10) phosphorus restriction appears to alter VDR metabolism through nongenomic mechanisms that are consistent with prolongation of the half-life of the receptor. Phosphorus vitamin D receptor Rattus norvegicus
8 The nature of the tissue-specific regulation of VDR during phosphorus restriction remains to be determined. Phosphorus vitamin D receptor Rattus norvegicus