Pub. Date : 1994 Nov-Dec
PMID : 7696547
20 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | rac-2,3-Dimercaptosuccinic acid (DMSA) was found to be superior to meso-2,3-dimercaptosuccinc acid in mobilizing in vivo heavy metals such as Cd, Hg, and Pb. | Succimer | Rac family small GTPase 2 | Homo sapiens | ||
| 2 | rac-2,3-Dimercaptosuccinic acid (DMSA) was found to be superior to meso-2,3-dimercaptosuccinc acid in mobilizing in vivo heavy metals such as Cd, Hg, and Pb. | Cadmium | Rac family small GTPase 2 | Homo sapiens | ||
| 3 | rac-2,3-Dimercaptosuccinic acid (DMSA) was found to be superior to meso-2,3-dimercaptosuccinc acid in mobilizing in vivo heavy metals such as Cd, Hg, and Pb. | Mercury | Rac family small GTPase 2 | Homo sapiens | ||
| 4 | rac-2,3-Dimercaptosuccinic acid (DMSA) was found to be superior to meso-2,3-dimercaptosuccinc acid in mobilizing in vivo heavy metals such as Cd, Hg, and Pb. | Lead | Rac family small GTPase 2 | Homo sapiens | ||
| 5 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | Succimer | Rac family small GTPase 2 | Homo sapiens | ||
| 6 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | Succimer | Rac family small GTPase 2 | Homo sapiens | ||
| 7 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | Succimer | Rac family small GTPase 2 | Homo sapiens | ||
| 8 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | Succimer | Rac family small GTPase 2 | Homo sapiens | ||
| 9 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | carboxylate | Rac family small GTPase 2 | Homo sapiens | ||
| 10 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | carboxylate | Rac family small GTPase 2 | Homo sapiens | ||
| 11 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | meso-dmsa | Rac family small GTPase 2 | Homo sapiens | ||
| 12 | The zinc complexes of rac-DMSA in aqueous solution are more stable than the corresponding complexes of its meso isomer because the rac-DMSA ligands always adopt staggered anti conformations, in which the electrostatic repulsion between two bulky carboxylate groups is minimized; in contrast, unlike in the crystal lattice, meso-DMSA ligands always adopt staggered gauche conformations in their zinc complexes. | meso-dmsa | Rac family small GTPase 2 | Homo sapiens | ||
| 13 | The conformations of various monomeric and dimeric zinc complexes with rac- and meso-2,3-dimercaptosuccinic acid in aqueous solution were determined by IR spectroscopy and proton NMR spectroscopy as a function of zinc:ligand ratio, by proton NMR spectroscopy as a function of pD, and by variable-temperature 13C NMR spectroscopy. | Palladium | Rac family small GTPase 2 | Homo sapiens | ||
| 14 | The conformations of various monomeric and dimeric zinc complexes with rac- and meso-2,3-dimercaptosuccinic acid in aqueous solution were determined by IR spectroscopy and proton NMR spectroscopy as a function of zinc:ligand ratio, by proton NMR spectroscopy as a function of pD, and by variable-temperature 13C NMR spectroscopy. | 13c | Rac family small GTPase 2 | Homo sapiens | ||
| 15 | rac-DMSA in ZnL2(6-) coordinates with zinc ion via two thiolate groups and one carboxylate group, whereas in Zn2L2(4-) each ligand complexes two zinc ions by using one carboxylate group and one thiolate group in the beta-position to bind to the same zinc ion. | Succimer | Rac family small GTPase 2 | Homo sapiens | ||
| 16 | rac-DMSA in ZnL2(6-) coordinates with zinc ion via two thiolate groups and one carboxylate group, whereas in Zn2L2(4-) each ligand complexes two zinc ions by using one carboxylate group and one thiolate group in the beta-position to bind to the same zinc ion. | thiolate | Rac family small GTPase 2 | Homo sapiens | ||
| 17 | rac-DMSA in ZnL2(6-) coordinates with zinc ion via two thiolate groups and one carboxylate group, whereas in Zn2L2(4-) each ligand complexes two zinc ions by using one carboxylate group and one thiolate group in the beta-position to bind to the same zinc ion. | carboxylate | Rac family small GTPase 2 | Homo sapiens | ||
| 18 | rac-DMSA in ZnL2(6-) coordinates with zinc ion via two thiolate groups and one carboxylate group, whereas in Zn2L2(4-) each ligand complexes two zinc ions by using one carboxylate group and one thiolate group in the beta-position to bind to the same zinc ion. | zn2l2 | Rac family small GTPase 2 | Homo sapiens | ||
| 19 | rac-DMSA in ZnL2(6-) coordinates with zinc ion via two thiolate groups and one carboxylate group, whereas in Zn2L2(4-) each ligand complexes two zinc ions by using one carboxylate group and one thiolate group in the beta-position to bind to the same zinc ion. | carboxylate | Rac family small GTPase 2 | Homo sapiens | ||
| 20 | rac-DMSA in ZnL2(6-) coordinates with zinc ion via two thiolate groups and one carboxylate group, whereas in Zn2L2(4-) each ligand complexes two zinc ions by using one carboxylate group and one thiolate group in the beta-position to bind to the same zinc ion. | thiolate | Rac family small GTPase 2 | Homo sapiens | ||