Title : [Preliminary studies on the effects of tumor necrosis factor gene transfer on the growth of human hepatocellular carcinoma cells in nude mice].

Pub. Date : 1995 May

PMID : 7656817






4 Functional Relationships(s)
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Protein Name
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1 An eukaryotic expression vector containing tumor necrosis factor alpha (TNF alpha) gene (psVK3-tnf) was transduced into hepatocellular carcinoma (HCC) cell line, SMMC7721, by calcium phosphate coprecipation method. calcium phosphate tumor necrosis factor Mus musculus
2 An eukaryotic expression vector containing tumor necrosis factor alpha (TNF alpha) gene (psVK3-tnf) was transduced into hepatocellular carcinoma (HCC) cell line, SMMC7721, by calcium phosphate coprecipation method. calcium phosphate tumor necrosis factor Mus musculus
3 An eukaryotic expression vector containing tumor necrosis factor alpha (TNF alpha) gene (psVK3-tnf) was transduced into hepatocellular carcinoma (HCC) cell line, SMMC7721, by calcium phosphate coprecipation method. calcium phosphate tumor necrosis factor Homo sapiens
4 Three weeks after the pSVK3-tnf DNA entrapped with calcium phosphate was introduced directly into subcutaneous nodules of human HCC in nude mice (treated mice), the growth of HCC was significantly delayed as compared to the pSVK3 group (control mice) (2.5 +/- 1.6 cm vs. 3.2 +/- 1.8 cm, n = 6, P < 0.05). calcium phosphate tumor necrosis factor Homo sapiens