Title : Inactivation of NF-kappa B inhibitor I kappa B alpha: ubiquitin-dependent proteolysis and its degradation product.

Pub. Date : 1995 Oct 4

PMID : 7575604






2 Functional Relationships(s)
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1 In this in vitro assay, ubiquitin, proteasome-containing S100 fraction and ATP are required for the proteolysis of I kappa B alpha. Adenosine Triphosphate NFKB inhibitor alpha Homo sapiens
2 We conclude that the inactivation of I kappa B alpha occurs through a series of processes including phosphorylation, ATP-dependent ubiquitin conjugation and proteasome-mediated proteolysis. Adenosine Triphosphate NFKB inhibitor alpha Homo sapiens