Title : Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

Pub. Date : 1995 Jan 15

PMID : 7531665






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Conclusive evidence has already shown that C/EBP alpha regulates terminal adipocyte differentiation, turning on the battery of fat-specific genes required for the synthesis, uptake, and storage of long chain fatty acids. long chain fatty acids CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus
2 Here we provide evidence that C/EBP delta and C/EBP beta play early catalytic roles in the differentiation pathway, relaying the effects of the hormonal stimulants DEX and MIX in a cascade-like fashion, leading to the activation of the gene encoding C/EBP alpha. Dexamethasone CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus