| Protein Name | CCAAT/enhancer binding protein alpha |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12606 |
| Gene Symbol | Cebpa |
| UniProt | P53566 (CEBPA_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
392
Total Number of Articles : 470 |
Description |
CCAAT/enhancer binding protein alpha |
| Gene Summary |
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. The use of alternative in-frame non-AUG (CUG) and AUG start codons results in several protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the CUG and the first AUG start codons. [provided by RefSeq, Sep 2014] |
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| Properties | |