Pub. Date : 1994 Jul 1
PMID : 7521071
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Experiments were performed to examine the effect of cyclic nucleotides on the expression of inducible nitric oxide synthase (iNOS) activity by interleukin-1 beta (IL-1 beta) treated rat aortic smooth muscle cells (SMC). | Nucleotides, Cyclic | nitric oxide synthase 2 | Rattus norvegicus |
| 2 | Experiments were performed to examine the effect of cyclic nucleotides on the expression of inducible nitric oxide synthase (iNOS) activity by interleukin-1 beta (IL-1 beta) treated rat aortic smooth muscle cells (SMC). | Nucleotides, Cyclic | nitric oxide synthase 2 | Rattus norvegicus |
| 3 | Similarly, lipophilic analogues of cAMP also induced both iNOS mRNA expression and nitrite release. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 4 | The addition of IL-1 beta and cAMP derivatives resulted in a synergistic enhancement of both iNOS mRNA production and of nitrite formation. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 5 | The capacity of cyclic nucleotides to positively modulate the induction of iNOS activity may play an important role in regulating the release of NO in vivo. | Nucleotides, Cyclic | nitric oxide synthase 2 | Rattus norvegicus |