Title : Inhibition of calcineurin by a novel FK-506-binding protein.

Pub. Date : 1994 Aug 19

PMID : 7520438






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 When complexed with FK-506, FKBP12.6 binds to and inhibits calcineurin, making it only the second FKBP discovered thus far to do so. Tacrolimus FKBP prolyl isomerase 1B Homo sapiens
2 The ability to inhibit calcineurin establishes the potential relevance of FKBP12.6 to the immunosuppressive or toxic side effects of FK-506. Tacrolimus FKBP prolyl isomerase 1B Homo sapiens