Title : Indapamide inhibits human platelet aggregation in vitro: comparison with hydrochlorothiazide.

Pub. Date : 1993

PMID : 7508063






3 Functional Relationships(s)
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1 Using isolated platelets, indapamide also inhibited aggregation induced by low doses of thrombin (70% inhibition with 0.035 U/ml). Indapamide coagulation factor II, thrombin Homo sapiens
2 Indapamide inhibited the thrombin-induced release of serotonin from dense granules by up to 80%. Indapamide coagulation factor II, thrombin Homo sapiens
3 Calcium mobilization evoked by thrombin stimulation and measured with the fluorescent dye Indo 1 was also reduced in presence of indapamide by 30%. Indapamide coagulation factor II, thrombin Homo sapiens