Title : Lipopolysaccharide treatment in vivo induces widespread tissue expression of inducible nitric oxide synthase mRNA.

Pub. Date : 1993 Nov 15

PMID : 7504469






2 Functional Relationships(s)
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1 The LPS-induced increase in iNOS mRNA was prevented by dexamethasone. Dexamethasone nitric oxide synthase 2 Rattus norvegicus
2 Our results indicate that LPS treatment in vivo induces the expression of an iNOS mRNA via a dexamethasone-sensitive mechanism, and thus provide direct molecular evidence for the involvement of NO in septic shock. Dexamethasone nitric oxide synthase 2 Rattus norvegicus