Title : The potential role of fibroblasts in periprosthetic osteolysis: fibroblast response to titanium particles.

Pub. Date : 1995 Sep

PMID : 7502715






2 Functional Relationships(s)
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1 Fibroblasts isolated from interfacial membranes of patients with failed total hip replacements and normal synovial tissue, when challenged with small-sized ( < 3 microns) titanium (Ti) particles, responded with significantly enhanced expressions of collagenase, stromelysin and, to a much lesser extent, their tissue inhibitor of metalloproteinases (TIMP). Titanium TIMP metallopeptidase inhibitor 1 Homo sapiens
2 Fibroblasts isolated from interfacial membranes of patients with failed total hip replacements and normal synovial tissue, when challenged with small-sized ( < 3 microns) titanium (Ti) particles, responded with significantly enhanced expressions of collagenase, stromelysin and, to a much lesser extent, their tissue inhibitor of metalloproteinases (TIMP). Titanium TIMP metallopeptidase inhibitor 1 Homo sapiens