Title : Glucocorticoids increase osteopontin expression in cardiac myocytes and microvascular endothelial cells. Role in regulation of inducible nitric oxide synthase.

Pub. Date : 1995 Nov 24

PMID : 7499354






1 Functional Relationships(s)
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1 However, osteopontin mRNA levels in heart muscle in vivo, and in cardiac myocytes and CMEC in vitro, also are increased 10-30-fold by the synthetic glucocorticoid dexamethasone, an agent that suppresses cytokine induction of NOS2 in both cell types. Dexamethasone nitric oxide synthase 2 Rattus norvegicus