Pub. Date : 1980
PMID : 7460794
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chronic administration of corticosterone (5 mg/kg) to developing rats induced an increase of tryptophan hydroxylase (TPH) activity in midbrain, but the responsivity of the enzyme to the steroid appeared to be limited only to a brief neonatal period (days 6-12). | Corticosterone | tryptophan hydroxylase 1 | Rattus norvegicus |
| 2 | Chronic administration of corticosterone (5 mg/kg) to developing rats induced an increase of tryptophan hydroxylase (TPH) activity in midbrain, but the responsivity of the enzyme to the steroid appeared to be limited only to a brief neonatal period (days 6-12). | Corticosterone | tryptophan hydroxylase 1 | Rattus norvegicus |
| 3 | Thus, the effect of the glucocorticoid and that of reserpine on TPH may involve different mechanisms. | Reserpine | tryptophan hydroxylase 1 | Rattus norvegicus |