Title : Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation.

Pub. Date : 1981 Aug

PMID : 6795624






2 Functional Relationships(s)
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1 However, comparison of 5-methylcytosine contents showed that J chain gene expression correlates with a loss of methyl groups. 5-Methylcytosine joining chain of multimeric IgA and IgM Homo sapiens
2 The primary encounter of a B cell with antigen must therefore trigger events that effect J chain gene transcription through a mechanism involving loss of methyl groups from cytosine. Cytosine joining chain of multimeric IgA and IgM Homo sapiens