Title : Quantitative structure-activity relationships and possible mechanisms of action of bispyridinium oximes as antidotes against pinacolyl methylphosphonofluoridate.

Pub. Date : 1983 Jul-Aug

PMID : 6628889






1 Functional Relationships(s)
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1 The antagonistic efficacy of these antidotes against pinacolyl methylphosphonofluoridate may be attributed to their direct antagonism at nicotinic receptor as well as reactivation of inhibited acetylcholinesterase. Soman acetylcholinesterase (Cartwright blood group) Homo sapiens