Title : The effects of razoxane (ICRF 159) on the production of collagenase and inhibitor (TIMP) by stimulated rabbit articular chondrocytes.

Pub. Date : 1983 Dec 15

PMID : 6318774






3 Functional Relationships(s)
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1 The effects of razoxane (ICRF 159) on the production of collagenase and inhibitor (TIMP) by stimulated rabbit articular chondrocytes. Razoxane TIMP metallopeptidase inhibitor 1 Homo sapiens
2 Collagenase production was inhibited and TIMP increased by Razoxane, in a dose-dependent manner, when cells were treated daily for 3 days. Razoxane TIMP metallopeptidase inhibitor 1 Homo sapiens
3 The results suggest that the ability of Razoxane to reduce collagenase and increase TIMP production may correlate with its effectiveness in treating psoriatic arthritis. Razoxane TIMP metallopeptidase inhibitor 1 Homo sapiens