Pub. Date : 1983 Jan
PMID : 6295180
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GMP would be broken down to guanosine by the enzyme 5"-nucleotidase on the cytoplasmic (extradiscal) surface of the disks. | guanosine 5'-monophosphorothioate | 5'-nucleotidase | Bos taurus |
| 2 | GMP would be broken down to guanosine by the enzyme 5"-nucleotidase on the cytoplasmic (extradiscal) surface of the disks. | Guanosine | 5'-nucleotidase | Bos taurus |
| 3 | The presence of 5"-nucleotidase on the cytoplasmic surface was verified by using sucrose continuous gradients to show its association with the photoreceptors and by using disk preparation and concanavalin A binding to demonstrate its presence on the extradiscal surface. | Sucrose | 5'-nucleotidase | Bos taurus |
| 4 | The 5"-nucleotidase on the extradiscal surface is light insensitive, has a broad optimal pH range, shows a divalent cation dependence, and is competitively inhibited by nucleoside di- and triphosphates. | nucleoside di- and triphosphates | 5'-nucleotidase | Bos taurus |
| 5 | When the data determined experimentally were extrapolated to physiological conditions, we obtained a decay time constant for GMP breakdown by 5"-nucleotidase in the range of 0.4 to 1.06 s. This time constant is in the range of the time constants of the fall of rod cell receptor potential, suggesting a possible role for GMP level in visual transduction. | guanosine 5'-monophosphorothioate | 5'-nucleotidase | Bos taurus |
| 6 | When the data determined experimentally were extrapolated to physiological conditions, we obtained a decay time constant for GMP breakdown by 5"-nucleotidase in the range of 0.4 to 1.06 s. This time constant is in the range of the time constants of the fall of rod cell receptor potential, suggesting a possible role for GMP level in visual transduction. | guanosine 5'-monophosphorothioate | 5'-nucleotidase | Bos taurus |