Title : In vitro activation of the contact (Hageman factor) system of plasma by heparin and chondroitin sulfate E.

Pub. Date : 1984 Jun

PMID : 6202346






3 Functional Relationships(s)
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1 In vitro activation of the contact (Hageman factor) system of plasma by heparin and chondroitin sulfate E. A large number of negatively charged macromolecules, including DNA, glycosaminoglycans, and proteoglycans, were tested as possible activators of the contact (Hageman factor) system in vitro. Heparin coagulation factor XII Rattus norvegicus
2 In vitro activation of the contact (Hageman factor) system of plasma by heparin and chondroitin sulfate E. A large number of negatively charged macromolecules, including DNA, glycosaminoglycans, and proteoglycans, were tested as possible activators of the contact (Hageman factor) system in vitro. Chondroitin Sulfates coagulation factor XII Rattus norvegicus
3 When the negative charge of the activating agents was blocked by the addition of hexadimethrine bromide, the cleavage of 125I-Hageman factor in the presence of prekallikrein was prevented. Hexadimethrine Bromide coagulation factor XII Rattus norvegicus