Title : Dexamethasone regulates the beta-adrenergic receptor subtype expressed by 3T3 L1 preadipocytes and adipocytes.

Pub. Date : 1982 Jun 25

PMID : 6123502






2 Functional Relationships(s)
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1 Subsequent treatment with 0.5 microM dexamethasone promoted the loss of beta-1 receptors, the appearance of beta-2 receptors, and a net 2- to 3-fold increase in the number of beta-receptors. Dexamethasone hemoglobin, beta adult major chain Mus musculus
2 Dexamethasone effected a complete switch from beta-1 to beta-2 subtype at concentrations as low as 2.5 nM while other steroids were ineffective below a concentration of 10 microM. Dexamethasone hemoglobin, beta adult major chain Mus musculus