Title : Cyclosporine blocks the induction of class I and class II MHC products in mouse kidney by graft-vs-host disease.

Pub. Date : 1985 Dec

PMID : 3864858






3 Functional Relationships(s)
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1 The ability of cyclosporine to prevent the increase in Ia and H-2K expression that occurs in mice with graft-vs-host disease (GVHD) was examined by means of absorption, indirect immunofluorescent staining (IIF), and indirect immunoperoxidase staining (IIP). Cyclosporine histocompatibility 2, K1, K region Mus musculus
2 Treatment with cyclosporine reduced the amount of donor Ia and H-2K in spleens, and prevented the enhanced expression of recipient Ia and H-2K in kidneys in a dose-dependent manner. Cyclosporine histocompatibility 2, K1, K region Mus musculus
3 Treatment with cyclosporine reduced the amount of donor Ia and H-2K in spleens, and prevented the enhanced expression of recipient Ia and H-2K in kidneys in a dose-dependent manner. Cyclosporine histocompatibility 2, K1, K region Mus musculus