Title : Gene expression during terminal differentiation: dexamethasone suppression of inducer-mediated alpha 1- and beta maj-globin gene expression.

Pub. Date : 1985 Aug

PMID : 3860841






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1 Gene expression during terminal differentiation: dexamethasone suppression of inducer-mediated alpha 1- and beta maj-globin gene expression. Dexamethasone hemoglobin, beta adult major chain Mus musculus
2 In this study, we show that dexamethasone blocks HMBA-mediated activation of alpha 1- and beta maj-globin gene transcription but not the induced chromatin change characterized by appearance of DNase I-hypersensitive regions upstream from the 5" cap sites of the alpha 1- and beta maj-globin genes. Dexamethasone hemoglobin, beta adult major chain Mus musculus
3 In this study, we show that dexamethasone blocks HMBA-mediated activation of alpha 1- and beta maj-globin gene transcription but not the induced chromatin change characterized by appearance of DNase I-hypersensitive regions upstream from the 5" cap sites of the alpha 1- and beta maj-globin genes. Dexamethasone hemoglobin, beta adult major chain Mus musculus