Title : C1- and C3-methyl-substituted derivatives of 7-hydroxy-2-(di-n-propylamino)tetralin: activities at central dopamine receptors.

Pub. Date : 1987 Oct

PMID : 3656358






1 Functional Relationships(s)
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1 C1- and C3-methyl-substituted derivatives of the potent dopamine (DA) receptor agonist 7-hydroxy-2-(di-n-propylamino)tetralin (7-OH-DPAT) have been synthesized, and their conformational preferences have been studied by use of NMR spectroscopy, X-ray crystallography, and molecular mechanics (MMP2) calculations. 7-hydroxy-2-N,N-dipropylaminotetralin matrix metallopeptidase 2 Rattus norvegicus