Title : Morphine in Combination with Ketamine Improves Cervical Cancer Pain and Suppresses Immune Function via the JAK3/STAT5 Pathway.

Pub. Date : 2022

PMID : 35492074






7 Functional Relationships(s)
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1 Morphine in Combination with Ketamine Improves Cervical Cancer Pain and Suppresses Immune Function via the JAK3/STAT5 Pathway. Morphine signal transducer and activator of transcription 5A Homo sapiens
2 Morphine in Combination with Ketamine Improves Cervical Cancer Pain and Suppresses Immune Function via the JAK3/STAT5 Pathway. Ketamine signal transducer and activator of transcription 5A Homo sapiens
3 Western blotting was used for detection of JAK3/STAT5 pathway-related proteins after naltrexone treatment in vitro. Naltrexone signal transducer and activator of transcription 5A Homo sapiens
4 The in vitro results demonstrated that the combination of morphine and ketamine may decrease CD4+ percentage, CD4+/CD8+ ratio, and the levels of IFN-gamma, IL-2, and IL-17 via the JAK3/STAT5 pathway. Morphine signal transducer and activator of transcription 5A Homo sapiens
5 The in vitro results demonstrated that the combination of morphine and ketamine may decrease CD4+ percentage, CD4+/CD8+ ratio, and the levels of IFN-gamma, IL-2, and IL-17 via the JAK3/STAT5 pathway. Ketamine signal transducer and activator of transcription 5A Homo sapiens
6 Conclusions: Our finding indicated that morphine-ketamine combination could improve cancer pain and repress immune function via the JAK3/STAT5 pathway in the progression of CC. Morphine signal transducer and activator of transcription 5A Homo sapiens
7 Conclusions: Our finding indicated that morphine-ketamine combination could improve cancer pain and repress immune function via the JAK3/STAT5 pathway in the progression of CC. Ketamine signal transducer and activator of transcription 5A Homo sapiens