Pub. Date : 2022 May
PMID : 35484202
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We report the crystal structure of a dislodged CTH of the ASK1-D3 mutant and demonstrate that disruptions in CTH plasticity via either CRISPR-Cas9 genome editing or expression of point mutation mutants result in impairment of SL signalling. | 3-Chloro-4-methylaniline hydrochloride | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 2 | We show that the conformational switch in ASK1-D3/MAX2 CTH directly regulates ubiquitin-mediated protein degradation. | 3-Chloro-4-methylaniline hydrochloride | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |