Title : Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells.

Pub. Date : 2022 Apr 8

PMID : 35396645






1 Functional Relationships(s)
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1 In contrast, sirtinol, an inhibitor of SIRT1, increases p65 acetylation, activates the NF-kappaB pathway, induces vascular smooth muscle cell transdifferentiation and senescence, and promotes vascular calcification. sirtinol v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus