Pub. Date : 2021 Dec 20
PMID : 34948431
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Therapeutics Response Portal (CTRP) analysis identified that Gemcitabine acted as a precision treatment for COAD when GDF15 expression was low. | gemcitabine | growth differentiation factor 15 | Homo sapiens |
2 | This study supports the miR-216a/GDF15 axis as a diagnostic/prognostic panel for COAD, identifies Th1, Treg, eosinophils, and NKTs as counteracting factors, indicates potential relationships underlying immunomodulation, mitochondrial organization, apoptotic signaling, and ER stress and unveil Gemcitabine as a potential drug for the development of treatment strategy when combined with targeting GDF15. | gemcitabine | growth differentiation factor 15 | Homo sapiens |