Pub. Date : 2022 Apr 1
PMID : 34838920
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To elucidate the potential role of Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling in the lung injury induced by short-term exposure of benzo(a)pyrene (BaP, a representative PAHs), intratracheally instilled mouse model was used and further interfered with its Wnt5a level by small molecule antagonists and agonists. | Benzo(a)pyrene | tafazzin, phospholipid-lysophospholipid transacylase | Mus musculus |
| 2 | Our findings together suggest that Wnt5a is a potential endogenous regulator in lung inflammation and airway epithelial injury, and Wnt5a-YAP/TAZ signaling contributes to lung dysfunction in acute exposure to BaP. | Benzo(a)pyrene | tafazzin, phospholipid-lysophospholipid transacylase | Mus musculus |