PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34838920-3 2022 To elucidate the potential role of Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling in the lung injury induced by short-term exposure of benzo(a)pyrene (BaP, a representative PAHs), intratracheally instilled mouse model was used and further interfered with its Wnt5a level by small molecule antagonists and agonists. Benzo(a)pyrene 155-158 wingless-type MMTV integration site family, member 5A Mus musculus 35-40 34838920-3 2022 To elucidate the potential role of Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling in the lung injury induced by short-term exposure of benzo(a)pyrene (BaP, a representative PAHs), intratracheally instilled mouse model was used and further interfered with its Wnt5a level by small molecule antagonists and agonists. Benzo(a)pyrene 155-158 yes-associated protein 1 Mus musculus 68-71 34838920-3 2022 To elucidate the potential role of Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling in the lung injury induced by short-term exposure of benzo(a)pyrene (BaP, a representative PAHs), intratracheally instilled mouse model was used and further interfered with its Wnt5a level by small molecule antagonists and agonists. Benzo(a)pyrene 155-158 tafazzin, phospholipid-lysophospholipid transacylase Mus musculus 72-75 34838920-3 2022 To elucidate the potential role of Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling in the lung injury induced by short-term exposure of benzo(a)pyrene (BaP, a representative PAHs), intratracheally instilled mouse model was used and further interfered with its Wnt5a level by small molecule antagonists and agonists. Benzo(a)pyrene 155-158 wingless-type MMTV integration site family, member 5A Mus musculus 263-268 34838920-4 2022 Our data revealed that BaP exposure induced the lung inflammatory response and reduced the expression of Clara cell secretory protein (CC16) in a dose-dependent manner. Benzo(a)pyrene 23-26 secretoglobin, family 1A, member 1 (uteroglobin) Mus musculus 105-133 34838920-4 2022 Our data revealed that BaP exposure induced the lung inflammatory response and reduced the expression of Clara cell secretory protein (CC16) in a dose-dependent manner. Benzo(a)pyrene 23-26 secretoglobin, family 1A, member 1 (uteroglobin) Mus musculus 135-139 34838920-6 2022 Functionally, inhibition of Wnt5a attenuated the BaP-induced inflammation and recuperated CC16 expression, as well as suppressed the epithelial cytokines release. Benzo(a)pyrene 49-52 wingless-type MMTV integration site family, member 5A Mus musculus 28-33 34838920-6 2022 Functionally, inhibition of Wnt5a attenuated the BaP-induced inflammation and recuperated CC16 expression, as well as suppressed the epithelial cytokines release. Benzo(a)pyrene 49-52 secretoglobin, family 1A, member 1 (uteroglobin) Mus musculus 90-94 34838920-8 2022 Our findings together suggest that Wnt5a is a potential endogenous regulator in lung inflammation and airway epithelial injury, and Wnt5a-YAP/TAZ signaling contributes to lung dysfunction in acute exposure to BaP. Benzo(a)pyrene 209-212 wingless-type MMTV integration site family, member 5A Mus musculus 35-40 34838920-8 2022 Our findings together suggest that Wnt5a is a potential endogenous regulator in lung inflammation and airway epithelial injury, and Wnt5a-YAP/TAZ signaling contributes to lung dysfunction in acute exposure to BaP. Benzo(a)pyrene 209-212 wingless-type MMTV integration site family, member 5A Mus musculus 132-137 34838920-8 2022 Our findings together suggest that Wnt5a is a potential endogenous regulator in lung inflammation and airway epithelial injury, and Wnt5a-YAP/TAZ signaling contributes to lung dysfunction in acute exposure to BaP. Benzo(a)pyrene 209-212 yes-associated protein 1 Mus musculus 138-141 34838920-8 2022 Our findings together suggest that Wnt5a is a potential endogenous regulator in lung inflammation and airway epithelial injury, and Wnt5a-YAP/TAZ signaling contributes to lung dysfunction in acute exposure to BaP. Benzo(a)pyrene 209-212 tafazzin, phospholipid-lysophospholipid transacylase Mus musculus 142-145