Title : Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity.

Pub. Date : 2022 Feb 1

PMID : 34784295






1 Functional Relationships(s)
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1 RNA sequencing uncovered that denatonium benzoate induced an NRF2-mediated nutrient stress response and an unfolded protein response that increased the expression of the mitokine GDF15 but also ADM2 and the LDLR, genes that are involved in anorectic signaling and lipid homeostasis. denatonium growth differentiation factor 15 Homo sapiens