Pub. Date : 2022 Jan
PMID : 34718940
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS AND RESULTS: In this context, we created a full-thickness excisional wound model in Wistar albino rats and, investigated NF-kappaB p65 DNA-binding activity and expression levels of RELA (p65), MMP2 and MMP9 in wound samples taken on days 0, 3, 7, and 14 from diabetic/non-diabetic rats treated with metformin and saline. | Metformin | matrix metallopeptidase 2 | Rattus norvegicus |
| 2 | As a result of our study, we showed that topically applied metformin accelerates wound healing by suppressing NF-kappaB p65 activity and diminishing the expression of MMP2 and MMP9. | Metformin | matrix metallopeptidase 2 | Rattus norvegicus |