Title : TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats.

Pub. Date : 2021 Nov

PMID : 34600915






2 Functional Relationships(s)
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1 Gelatin zymography and Western blots revealed decreases in MMP-2 and MMP-9 and increases in MMP-1 and MMP-7 in aorta, uterus and placenta of Preg+TNFalpha and RUPP, that were reversed in RUPP+Etanercept rats. rupp matrix metallopeptidase 2 Rattus norvegicus
2 Gelatin zymography and Western blots revealed decreases in MMP-2 and MMP-9 and increases in MMP-1 and MMP-7 in aorta, uterus and placenta of Preg+TNFalpha and RUPP, that were reversed in RUPP+Etanercept rats. rupp matrix metallopeptidase 2 Rattus norvegicus