Title : Combination Therapy of Navitoclax with Chemotherapeutic Agents in Solid Tumors and Blood Cancer: A Review of Current Evidence.

Pub. Date : 2021 Aug 28

PMID : 34575429






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ABT-263, known as navitoclax, mimics the BH3-only proteins of the BCL-2 family and has a high affinity towards pro-survival BCL-2 family proteins (i.e., BCL-XL, BCL-2, BCL-W) to induce cell apoptosis effectively. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 apoptosis regulator Homo sapiens
2 ABT-263, known as navitoclax, mimics the BH3-only proteins of the BCL-2 family and has a high affinity towards pro-survival BCL-2 family proteins (i.e., BCL-XL, BCL-2, BCL-W) to induce cell apoptosis effectively. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 apoptosis regulator Homo sapiens
3 ABT-263, known as navitoclax, mimics the BH3-only proteins of the BCL-2 family and has a high affinity towards pro-survival BCL-2 family proteins (i.e., BCL-XL, BCL-2, BCL-W) to induce cell apoptosis effectively. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 like 1 Homo sapiens
4 ABT-263, known as navitoclax, mimics the BH3-only proteins of the BCL-2 family and has a high affinity towards pro-survival BCL-2 family proteins (i.e., BCL-XL, BCL-2, BCL-W) to induce cell apoptosis effectively. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 apoptosis regulator Homo sapiens
5 ABT-263, known as navitoclax, mimics the BH3-only proteins of the BCL-2 family and has a high affinity towards pro-survival BCL-2 family proteins (i.e., BCL-XL, BCL-2, BCL-W) to induce cell apoptosis effectively. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 like 2 Homo sapiens